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The Thermogenic Effect of Thyroid Hormone and Its Clinical Implications

Physiology in Medicine review article An explanation of the thyroid, thyrotoxicosis and thermogenic effects and mechanisms of the thyroid hormone. Thyrotoxicosis is usually associated with weight loss and heat intolerance. Cold intolerance, but not weight gain, is a prominent feature of hypothyroidism. The thermogenic effect of thyroid hormones is closely linked to increased appetite and lipogenesis to ensure fuel availability and avoid wasting.

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