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Miniature Transmitter Release: Accident of Nature or Careful Design?

Miniature transmitter release results from the constitutive low-level release of individual vesicles of neurotransmitter. Since the 1950s, this form of synaptic transmission has largely been thought to reflect a leaky evoked-release mechanism, and it was not clear whether it had a function of its own. Recent data challenge this view and suggest that miniature release can affect both the local chemistry of synapses and the network properties of neurons.

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Classifications


Resource Type: Diagram, Illustration, Journal article/Issue, Review
Audience Level: Undergraduate upper division 15-16, Graduate, Professional (degree program)

Author and Copyright


Authors and Editors: Yo Otsu of Kinsmen Laboratory and Brain Research Centre, University of British Columbia, Timothy H. Murphy of Kinsmen Laboratory and Brain Research Centre, University of British Columbia
Publisher: American Association for the Advancement of Science
Format: application/pdf, image/gif, image/jpeg, text/html
Copyright and other restrictions: Yes
Cost: Yes

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