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Propelling Progeny

The capacity of a virus to disseminate through its host is a key determinant of virulence; however, until recently, relatively little information on the molecular mechanisms used by viruses to accomplish this has been available. This perspective discusses a report by Doceul et al., who propose that poxviruses spread within a host by inducing infected cells to propel progeny virions along their cell surfaces, and across those of neighboring newly infected cells, until they reach the surfaces of uninfected cells.

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Resource Type: Journal article/Issue, Illustration
Audience Level: High school upper division 11-12, Undergraduate lower division 13-14, Undergraduate upper division 15-16, Graduate, Professional (degree program), Continuing education

Author and Copyright

Authors and Editors: David Pickup of Department of Molecular Genetics and Microbiology, Duke University Medical Center
Publisher: AAAS
Format: text/html
Copyright and other restrictions: Yes
Cost: No


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