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Alchemy in the Soup: Transforming Metabolic Signals to Excitability

The intersection of cell metabolism with electrical signaling links the environment and cell function over time scales ranging from milliseconds to lifetimes. In responding to cellular metabolites, adenosine triphosphate (ATP)–sensitive potassium (KATP) channels are an important component of this intersection. Recent studies have begun to delineate the roles of KATP channels in multiple tissues and the far-reaching consequences of aberrant KATP channel activity and disturbed sensing of cell metabolism.

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Resource Type: Bibliography, Diagram, Illustration, Journal article/Issue, Review
Audience Level: Undergraduate upper division 15-16, Graduate, Professional (degree program)

Author and Copyright

Authors and Editors: Colin G. Nichols of Department of Cell Biology and Physiology, Washington University School of Medicine
Publisher: American Association for the Advancement of Science
Format: application/pdf, image/gif, image/jpeg, text/html
Copyright and other restrictions: Yes
Cost: Yes


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