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Receptor Cross Talk: Ligand-Gated Ion Channels Start to Communicate

Evidence is mounting for a direct mode of interaction between neurotransmitter receptors that modulates the activity of the interacting proteins. Brandon and Moss discuss two examples in which direct interactions between neurotransmitter receptors appear to regulate the receptors independently of the signal transduction cascades they activate. This type of interaction has important implications for rapid modulation of receptor function and the integration of multiple signals at a synapse.

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Classifications


Resource Type: Bibliography, Diagram, Illustration, Journal article/Issue, Review
Audience Level: Undergraduate upper division 15-16, Graduate, Professional (degree program)

Author and Copyright


Authors and Editors: Nicholas J. Brandon of Medical Research Council Laboratory of Molecular Cell Biology and Department of Pharmacology, University College London, Stephen J. Moss of Medical Research Council Laboratory of Molecular Cell Biology and Department of Pharmacology, University College London
Publisher: American Association for the Advancement of Science
Format: application/pdf, image/gif, image/jpeg, text/html
Copyright and other restrictions: Yes
Cost: Yes

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Collection:
STKE/Science Signaling


     
   

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