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Cyclic ADP Ribose as a Calcium-Mobilizing Messenger

This Perspective by Galione and Churchill is one in a series on intracellular calcium release mechanisms. The authors review the evidence for cyclic adenosine diphosphate ribose (cADPR) being a second messenger involved in regulating intracellular calcium. In addition, the physiological stimuli and responses mediated by cADPR are discussed. The Perspective is accompanied by a movie showing a calcium wave triggered by cADPR.

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Resource Type: Animation, Bibliography, Diagram, Illustration, Journal article/Issue, Review, Table
Audience Level: Undergraduate upper division 15-16, Graduate, Professional (degree program)

Author and Copyright

Authors and Editors: Antony Galione of University of Oxford, Department of Pharmacology, Grant C. Churchill of University of Oxford, Department of Pharmacology
Publisher: American Association for the Advancement of Science
Format: application/pdf, application/x-shockwave-flash, image/gif, image/jpeg, text/html
Copyright and other restrictions: Yes
Cost: Yes


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