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Highlights of Alternative Splicing Regulation Session: Yes, No, Maybe--A History of Paradigm Shifts

Cooper summarizes the discussions and presentations from the session entitled "Control of Splice Site Selection" held at the Sixth Annual Meeting of the RNA Society. Paradigms are shifting as experiments show that some of the proteins involved in regulating splicing can act as splicing enhancers or repressors, depending on the cellular context. The complex interactions among the ribonucleoproteins (RNPs) and proteins, and the role of cis elements, in controlling cell-specific splicing are highlighted. The importance of properly regulated splicing is emphasized by examples of disease pathologies in which alternative splicing is aberrant.

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Classifications


Resource Type: Diagram, Illustration, Journal article/Issue, Report
Audience Level: Undergraduate upper division 15-16, Graduate, Professional (degree program)

Author and Copyright


Authors and Editors: Thomas A. Cooper of Departments of Pathology and Molecular and Cellular Biology, Baylor College of Medicine
Publisher: American Association for the Advancement of Science
Format: application/pdf
Copyright and other restrictions: Yes
Cost: Yes

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STKE/Science Signaling


     
   

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