SIGN IN   Advanced Search

Browse Review
CELL BIOLOGY: Fats, Flies, and Palmitate

Access to the article is free, however registration and sign-in are required. Biologists have long pondered how animal cells regulate the composition of their complex lipid membranes. In their Perspective, Nohturfft and Losick discuss new work (Dobrosotskaya et al.) that solves another piece of the puzzle. Flies and mammals share a similar feedback pathway for lipid synthesis that depends on controlling the proteolysis of sterol response element binding protein. The new work shows that in flies, cleavage of this protein depends on a membrane phospholipid sensor, phosphatidylethanolamine.

Rate this Resource:
1 = not useful, 5 = very useful

Please be the first to rate this resource.

View Free


Resource Type: Journal article/Issue, Review, Diagram
Audience Level: Undergraduate lower division 13-14, Undergraduate upper division 15-16, Graduate

Author and Copyright

Authors and Editors: Axel Nohturfft of Department of Molecular and Cellular Biology, Harvard University, Richard Losick of Department of Molecular and Cellular Biology, Harvard University
Publisher: AAAS
Format: text/html
Copyright and other restrictions: Yes
Cost: No


» Sign In or register to post comments.

American Association for the Advancement of Science



Triple A S National Science Foundation Naitonal Science Digital Library Pathway
Funded by the individual BEN Collaborators and grants from the
National Science Foundation [DUE 0085840 / DUE 0226185 / DUE 0532797 / DUE 0734995]

This website is a National Science Digital Library (NSDL) Pathway.
Copyright © 2019. American Association for the Advancement of Science. All Rights Reserved.