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CELL BIOLOGY: Caveolae--Not Just Craters in the Cellular Landscape

Caveolae are small invaginations in the plasma membrane of mammalian cells that seem to be important for signal transduction and uptake of macromolecules. According to Shin and Abraham in their Perspective, recent work reveals that these cellular craters have been commandeered by pathogens and bacterial toxins, enabling them to gain entry to host cells while avoiding the perils of classic endocytosis and the lysosomal degradation pathway.

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Resource Type: Journal article/Issue, Review, Diagram
Audience Level: Undergraduate lower division 13-14, Undergraduate upper division 15-16, Graduate

Author and Copyright

Authors and Editors: Jeoung-Sook Shin of Departments of Pathology and Microbiology, Duke University Medical Center, Soman N. Abraham of Departments of Pathology and Microbiology, Duke University Medical Center
Publisher: AAAS
Format: text/html
Copyright and other restrictions: Yes
Cost: No


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