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VIROLOGY: Even Viruses Can Learn to Cope with Stress

Access to the article is free, however registration and sign-in are required. When a virus infects a cell, cellular defense mechanisms are activated, sometimes even causing cell death in an effort to stem the infection. As McFadden explains in his commentary, the virus in turn marshals its own countermeasures, striving to keep the cell alive so the virus can replicate and spread. A report by Schisler et al. shows how one of these countermeasures--synthesis of glutathione synthase, which protects cells against oxidative damage--is used by molluscum contagiosum virus and synthesized by a unique translation control mechanism for selenoproteins.

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Resource Type: Journal article/Issue, Review, Diagram
Audience Level: Undergraduate lower division 13-14, Undergraduate upper division 15-16, Graduate

Author and Copyright

Authors and Editors: Grant McFadden of John P. Robarts Research Institute and the Department of Microbiology and Immunology, University of Western Ontario
Publisher: AAAS
Format: text/html
Copyright and other restrictions: Yes
Cost: No


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