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Part 2: Details of DNA Repair in Budding Yeast

A specific set of examples of homologous recombination in budding yeast is presented based primarily on data from the Haber lab. Here a site-specific HO endonuclease can be induced to create a single DSB in the genome and the kinetics of repair can be followed in real time. The roles of key recombination proteins and the different types of outcomes provoked by this DSB are reviewed.

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Classifications


Resource Type: Lecture/Lecture outline, Video
Audience Level: High school upper division 11-12, Undergraduate lower division 13-14, Undergraduate upper division 15-16

Author and Copyright


Authors and Editors: Jim Haber of Department of Biology and Rosenstiel Basic Medical Sciences Research Center, Brandeis University
Publisher: iBioSeminars
Format: text/html
Copyright and other restrictions: Yes
Cost: No

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