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SIGNAL TRANSDUCTION: Hot and Cold TRP Ion Channels

Access to the article is free, however registration and sign-in are required. Tasting menthol evokes a cool sensation. In his Perspective, Clapham discusses new work published elsewhere that identifies a TRP ion channel, which is opened by both cold temperature and menthol. The channel is expressed in neurons of the trigeminal and dorsal root ganglia that receive sensations from regions such as the mouth and in the skin.

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Resource Type: Journal article/Issue, Review, Image
Audience Level: Undergraduate lower division 13-14, Undergraduate upper division 15-16, Graduate

Author and Copyright

Authors and Editors: David E. Clapham of Howard Hughes Medical Institute, Harvard Medical School
Publisher: AAAS
Format: text/html
Copyright and other restrictions: Yes
Cost: No


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