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Specifying and Sustaining Pigmentation Patterns in Domestic and Wild Cats

Common patterns found in cheetahs and house cats suggest a shared mechanism for creating their parti-colored coats. In this paper, Kaelin et al. use histology, genomic expression studies, and transgenic mice to unravel the relationship between the Taqpep gene and periodic coat patterns in felids.

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Resource Type: Report, Image, Educational standards, Lesson plan
Audience Level: High school upper division 11-12, Undergraduate lower division 13-14, Undergraduate upper division 15-16, Graduate, Professional (degree program), General public & informal education

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Authors and Editors: Christopher B. Kaelin of Stanford University, HudsonAlpha Institute for Biotechnology, Xiao Xu of Sichuan University, Frederick National Laboratory for Cancer Research, Lewis Z. Hong of Department of Genetics, Stanford University, Victor A. David of Laboratory of Genomic Diversity, Frederick National Laboratory for Cancer Research, Kelly A. McGowan of Department of Genetics, Stanford University, Anne Schmidt-Kuntzel of Cheetah Conservation Fund, Frederick National Laboratory for Cancer Research, Melody E. Roelke of Laboratory of Genomic Diversity, Frederick National Laboratory for Cancer Research, Javier Pino of Department of Biological Sciences, Florida International University, Joan Pontius of Laboratory of Genomic Diversity, Frederick National Laboratory for Cancer Research, Gregory M. Cooper of HudsonAlpha Institute for Biotechnology, Hermogenes Manuel of Department of Genetics, Stanford University, William F. Swanson of Center for Conservation and Research of Endangered Wildlife, Cincinnati Zoo & Botanical Garden, Laurie Marker of Cheetah Conservation Fund, Cindy K. Harper of Veterinary Genetics Laboratory, Faculty of Veterinary Science Onderstepoort, Ann Van Dyk of University of Pretoria, Bisong Yue of Sichuan Key Laboratory of Conservation Biology on Endangered Wildlife, Pretoria, James C. Mullikin of College of Life Sciences, The Ann van Dyk Cheetah Centre, Wesley C. Warren of Comparative Genomics Unit, Sichuan University, Eduardo Eizirik of National Human Genome Research Institute, National Institutes of Health, Lidia Kos of The Genome Center, Washington University in St. Louis, Stephen J. O'Brien of Instituto Pró-Carnívoros, Pontifícia Universidade Católica do Rio Grande do Sul, Gregory S. Barsh of Department of Biological Sciences, Porto Alegre, Marilyn Menotti-Raymond of Laboratory of Genomic Diversity, Florida International University
Publisher: SCIENCE
Format: text/html
Copyright and other restrictions: Yes
Cost: No

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