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CELL BIOLOGY: A Cellular Striptease Act

Access to the article is free, however registration and sign-in are required. Proteins on the cell surface can be cleaved by proteolytic enzymes. In the Perspective, Werb and Yan outline the many purposes of these cleavage events-to provide ligand for binding to receptors (as shown in the report by Peschon et al. on p. 1281), to eliminate ligand on receptors and to increase or decrease cell-cell interactions. Such proteolysis can be regulated and is turning out to be widely used by the cell.

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Resource Type: Journal article/Issue, Review, Diagram
Audience Level: Undergraduate lower division 13-14, Undergraduate upper division 15-16, Graduate

Author and Copyright

Authors and Editors: Zena Werb of Department of Anatomy, University of California, Yibing Yan of Department of Anatomy, San Francisco
Publisher: AAAS
Format: text/html
Copyright and other restrictions: Yes
Cost: No


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