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BIOCHEMISTRY: Directing Biosynthesis

Access to the article is free, however registration and sign-in are required. Genetic engineering is revealing biosynthetic pathways for the synthesis of small molecules and avenues toward cheaper syntheses. Projects aiming to direct the biosynthesis of small molecules may seek to make new compounds, make natural compounds in unnatural organisms, or alter the metabolic flux through a particular biosynthetic pathway. This Perspective presents three examples that illustrate the state of directed biosynthesis and highlight its future prospects.

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Resource Type: Journal article/Issue, Review, Diagram
Audience Level: High school upper division 11-12, Undergraduate lower division 13-14, Undergraduate upper division 15-16, Graduate

Author and Copyright

Authors and Editors: Michael A. Fischbach of Harvard University, Harvard Medical School, Christopher T. Walsh of Department of Biological Chemisty and Molecular Pharmacology, Harvard Medical School
Publisher: AAAS
Format: text/html
Copyright and other restrictions: Yes
Cost: No


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