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STRUCTURAL BIOLOGY: Breaching the Barrier

Access to the article is free, however registration and sign-in are required. There are a huge number of membrane transporter proteins that transport molecules across the impermeable barrier presented by cellular membranes. In their Perspective, Locher et al. discuss a double tour de force (Abramson et al., Huang et al.), which provide structural determinations of two bacterial transporters, LacY and GlpT, and insights into how they work.

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Classifications


Resource Type: Journal article/Issue, Review, Diagram
Audience Level: High school upper division 11-12, Undergraduate lower division 13-14, Undergraduate upper division 15-16, Graduate

Author and Copyright


Authors and Editors: Kaspar P. Locher of Institut für Molekularbiologie und Biophysik, Eidgenössische Technische Hochschule Zürich, Randal B. Bass of Division of Chemistry and Chemical Engineering, California Institute of Technology, Douglas C. Rees of Division of Chemistry and Chemical Engineering, California Institute of Technology
Publisher: AAAS
Format: text/html
Copyright and other restrictions: Yes
Cost: No

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