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BMP-1: Resurrection As Procollagen C-Proteinase

Access to the article is free, however registration and sign-in are required. The characterization of the function of bone morphogenetic protein-1 (BMP-1) was reported in last week's issue of Science (19 January, p. 360). In his Perspective, A. H. Reddi explains why it was surprising (and important) that BMP-1 turned out to be identical to procollagen C-proteinase, the enzyme responsible for triggering the self-assembly of collagen.

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Resource Type: Journal article/Issue, Review, Diagram
Audience Level: High school upper division 11-12, Undergraduate lower division 13-14, Undergraduate upper division 15-16, Graduate

Author and Copyright

Authors and Editors: A. H. Reddi of Departments of Orthopedic Surgery and Biological Chemistry, Johns Hopkins University School of Medicine
Publisher: AAAS
Format: text/html
Copyright and other restrictions: Yes
Cost: No


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