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BIOMEDICINE: Contact--How Platelets Touch von Willebrand Factor

Access to the article is free, however registration and sign-in are required. The initiation of clotting at sites of vascular injury involves the adhesion of platelets to von Willebrand factor (VWF) via the surface glycoprotein GPIba. In a Perspective, Sadler discusses a new structural analysis (Huizinga et al.) that sheds light on how platelet GPIba interacts with VWF.

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Resource Type: Journal article/Issue, Review, Image
Audience Level: Undergraduate lower division 13-14, Undergraduate upper division 15-16, Graduate

Author and Copyright

Authors and Editors: J. Evan Sadler of Department of Medicine, Washington University School of Medicine
Publisher: AAAS
Format: text/html
Copyright and other restrictions: Yes
Cost: No


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