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BIOCHEMISTRY: How Iron Activates O2

Access to the article is free, however registration and sign-in are required. Iron enzymes play a key role in many biological processes involving oxygen, from the biosynthesis of DNA to the conversion of electrochemical to chemical energy. In her Perspective, Kovacs highlights two reports that shed light on some of the intermediates that may be involved in reactions promoted by nonheme iron enzymes. Rohde et al. study a chemical analog system, while Karlsson et al. investigate the enzyme naphthalene dioxygenase with x-ray crystallography. By catching some of the fleeting intermediates, the two studies help to understand the enzymatic mechanism of this important group of proteins.

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Classifications


Resource Type: Journal article/Issue, Review, Image
Audience Level: Undergraduate lower division 13-14, Undergraduate upper division 15-16, Graduate

Author and Copyright


Authors and Editors: Julie A. Kovacs of Department of Chemistry, University of Washington
Publisher: AAAS
Format: text/html
Copyright and other restrictions: Yes
Cost: No

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Collection:
American Association for the Advancement of Science


     
   

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