SIGN IN   Advanced Search

Browse Enzymology
APOPTOSIS: A Cinderella Caspase Takes Center Stage

Access to the article is free, however registration and sign-in are required. It has been thought that permeabilization of mitochondria and release of cytochrome c is an early event in apoptosis that is required for activation of caspases, the enzyme executioners of the apoptotic cascade. However, in a Perspective, Kumar and Vaux explain new findings (Lassus et al.) that implicate an often ignored caspase, caspase-2, in the early stages of apoptosis prior to mitochondrial permeabilization.

Rate this Resource:
1 = not useful, 5 = very useful

Please be the first to rate this resource.

View Free


Resource Type: Journal article/Issue, Review, Diagram
Audience Level: Undergraduate lower division 13-14, Undergraduate upper division 15-16, Graduate

Author and Copyright

Authors and Editors: Sharad Kumar of Hanson Institute, David L. Vaux of Walter and Eliza Hall Institute
Publisher: AAAS
Format: text/html
Copyright and other restrictions: Yes
Cost: No


» Sign In or register to post comments.

American Association for the Advancement of Science



Triple A S National Science Foundation Naitonal Science Digital Library Pathway
Funded by the individual BEN Collaborators and grants from the
National Science Foundation [DUE 0085840 / DUE 0226185 / DUE 0532797 / DUE 0734995]

This website is a National Science Digital Library (NSDL) Pathway.
Copyright © 2019. American Association for the Advancement of Science. All Rights Reserved.