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A Revolving Door for Calcium

Mitochondria are subcellular organelles that produce energy in the form of adenosine 5′-triphosphate (ATP) in response to chemical cues. This perspective discusses a report by Jiang et al., who show that leucine zipper EF hand–containing transmembrane protein 1 (Letm1) is one of the elusive Ca2+-transport proteins. The transporter may be a good candidate for the pathogenesis of Wolf-Hirschhorn syndrome, a severe human neurological disease characterized by mental retardation and seizures.

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Resource Type: Journal article/Issue, Illustration
Audience Level: Undergraduate lower division 13-14, Undergraduate upper division 15-16, Graduate, Professional (degree program), Continuing education

Author and Copyright

Authors and Editors: Nicolas Demaurex of Department of Cell Physiology and Metabolism, University of Geneva, Damon Poburko of Department of Cell Physiology and Metabolism, University of Geneva
Publisher: SCIENCE
Format: text/html
Copyright and other restrictions: Yes
Cost: No


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