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Phosphodiesterases Maintain Signaling Fidelity via Compartmentalization of Cyclic Nucleotides

Novel technological advances have improved our understanding of how cyclic nucleotides are able to convey signals faithfully between cellular compartments. Phosphodiesterases play a crucial role in shaping these signals in health and disease. The concept of compartmentalization is guiding the search for therapies that have the potential to offer greater efficacy and tolerability compared with current treatments.

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Resource Type: Journal Article/Issue
Audience Level: Undergraduate lower division (Grades 13-14), Undergraduate upper division (Grades 15-16), Graduate, Professional (degree program), General Public, Informal Education, Continuing Education

Author and Copyright


Authors and Editors: Oliver Lomas of University of Oxford, Manuela Zaccolo of University of Oxford
Format: text/html
Copyright and other restrictions: No
Cost: No

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Collection:
American Physiological Society


     
   

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